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The Relationship between cAMP (Cyclic Adenosine Monophosphate) and Criminal Aspects of Murder
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Issa Layali *1    , Abolfazl Sadeghi2 , Ayda Seyed Noormand Hiagh3 , Hanie Rostami2 , Mohamaad Hossein Vali2 , Nooshin Soltani2 |
1- Department of Biochemistry and Biophysics, TeMS.C., Islamic Azad University, Tehran, Iran.
2- Department of Medical Law, Tehran Medical Sciences Branch, Islamic Azad University, Tehran, Iran.
3- Department of Biochemistry and Biophysics, Tehran Medical Sciences Branch, Islamic Azad University, Tehran, Iran. |
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Abstract: (116 Views) |
Background and Aim: Cyclic adenosine monophosphate (cAMP) is one of the biological molecules in regulating brain behavior and function and its level can be associated with the occurrence of impulsive, aggressive and violent behaviors. In recent years, experimental research in the fields of biology and clinical psychiatry has identified the role of intracellular messengers in criminal behavior patterns. This article seeks to answer the question of whether fluctuations or disruptions in cAMP levels can be effective in analyzing the motivation, criminal responsibility or rehabilitative capacity of murderers.
Methods: This study was conducted using a descriptive-analytical method and a review of reputable scientific sources in PubMed, Scopus and Science Direct and Google Scholar databases. It attempts to investigate the possible role of cAMP levels as a complementary biomarker alongside clinical assessments in criminal proceedings through biochemical and behavioral data.
Ethical Considerations: In all stages of writing the present research, while respecting the originality of the texts, honesty and trustworthiness have been observed.
Results: The findings indicate that although cAMP plays a role in regulating behavior, it cannot be considered the basis for determining criminal responsibility or identifying the motive for a crime alone, unless it is used within the framework of scientific and legal criteria, along with other psychiatric, social and legal data.
Conclusion: As a result, the legal use of biomarkers such as cAMP must be accompanied by consideration of interpretative limitations, the individuality of the accused and the principles of fair trial. |
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| Keywords: cAMP, Murder, Impulsive and Violent Behavior, cAMP/CREB Pathway |
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Full-Text [PDF 621 kb]
(59 Downloads)
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Type of Study: Review Article |
Received: 2024/11/20 | Accepted: 2025/02/10 | Published: 2025/03/15
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